The Journal of Organic Chemistry

Base-Catalyzed Ring Opening of Diethyl 1, 1, 2, 2-Tetracyanocyclopropane-3, 3-dicarboxylate

TH Regan

Index: Regan,T.H. Journal of Organic Chemistry, 1962 , vol. 27, p. 2236 - 2237

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Citation Number: 6

Abstract

Polycarboxylic esters of cyclopropane are generally stable to bases with respect to ring c1eavage. l Hydrolysis is often accompanied by decarboxylation but the cyclopropane ring remains intact unless very vigorous reaction conditions are employed. Herewith is reported an example of a cyclopropane ring cleavage under very mild conditions. Diethyl 1, 1, 2, 2- tetracyanocyclopropane-3, 3-dicarboxylate (I) was synthesized using the technique of ...