Synthetic Communications

Synthetic Reactions by Complex Catalysts. XXII. Copper-Catalyzed Reaction of Isonitrile with Active Methylene Compounds

T Saegusa, I Murase, Y Ito

Index: Saegusa,T. et al. Synthetic Communications, 1971 , vol. 1, p. 145 - 152

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Citation Number: 3

Abstract

Abstract In previous papers2–6) we have reported the copper catalyzed reactions of isonitrile with various RQH compounds, in which the terminal carbon atom of isonitrile is inserted between heteroatom-hydrogen bonds, ie, NH bond of amine, PH of phosphine, OH of alcohol, SH of thiol and Si-H of silane,(eq. 1). In these reactions, the derivatives of hypothetical “fonirnidfc acid”, HC ([dbnd] NR) OH, are produced in high yields. These ...