Copper??Catalyzed Aerobic Dehydrogenative Cyclization of N??Methyl??N??phenylhydrazones: Synthesis of Cinnolines

G Zhang, J Miao, Y Zhao, H Ge

Index: Zhang, Guangwu; Miao, Jinmin; Zhao, Yan; Ge, Haibo Angewandte Chemie - International Edition, 2012 , vol. 51, # 33 p. 8318 - 8321

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Citation Number: 65

Abstract

Selective carbon–carbon (CÀC) bond formation is one of the most important processes in organic chemistry since it enables key steps in the synthesis of complex organic molecules from simple precursors. Traditionally, the construction of CÀC bonds relies primarily on prefunctionalized substrates, which usually requires additional synthetic steps, and thus reduces the overall efficiency of this transformation.[1] For this reason, CÀC bond ...