Benzylamide derivative compound attenuates the ultraviolet B-induced hyperpigmentation in the brownish guinea pig skin

SY Choi, S Kim, JS Hwang, BG Lee, H Kim…

Index: Choi, Sang Yoon; Kim, Sanghee; Hwang, Jae Sung; Lee, Byeong Gon; Kim, Hocheol; Kim, Sun Yeou Biochemical Pharmacology, 2004 , vol. 67, # 4 p. 707 - 715

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Citation Number: 35

Abstract

This study evaluated the effects of synthetic benzylamide compound I (2, 6-dimethoxy-N- phenylbenzamide) on the ultraviolet B (UV B)-induced hyperpigmentation of the skin. UV B- induced hyperpigmentation was elicited on brownish guinea pig skin according to the method reported by Hideya et al.[Arch Dermatol Res 290 (1998) 375] with minor modifications. A lightening effect was observed following the topical application of ...