Many tetrahydroquinolines with biologically interesting properties have been discovered in the past few years, and they have been investigated as drug candidates against type II diabetes,11. Borella , C. , Foley , K. , Sun , L. , Chim??Manamada , DU , Li , H. , Xia , Z. , Vo , N. , Bohnert , G. , Chen , S. and Wu , Y. Tetrahydroquinolines for Prevention and Treatment of Metabolic Disorders. PCT. Int. Appl. WO 2006065842, 2006.