Tetrahedron

The study of intramolecular tandem radical cyclizations of acylsilanes with radicalphiles attached on silicon

KH Tang, FY Liao, YM Tsai

Index: Tang, Kuo-Hsiang; Liao, Fang-Yu; Tsai, Yeun-Min Tetrahedron, 2005 , vol. 61, # 8 p. 2037 - 2045

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Citation Number: 14

Abstract

Radical cyclizations of acylsilanes with radicalphilic pendant introduced on silicon proceeded in a tandem fashion to give spiro products containing a cyclic silyl ether skeleton. Because the alkoxysilyl group can be replaced with a hydroxy group through oxidation, the spiro silyl ethers can be converted into diols. In the case with a radical intermediate carrying 2-oxa-3-sila-6-heptenyl skeleton, products derived from 1, 7-endo cyclization were ...