… to the synthesis of eudesmane and elemane sesquiterpene lactones. Total synthesis of dl-dihydrocallitrisin, dl-7, 8-epialantolactone, dl-7, 8-epiisoalantolactone, and …

AG Schultz, JD Godfrey

Index: Schultz, Arthur G.; Godfrey, Jollie D. Journal of the American Chemical Society, 1980 , vol. 102, # 7 p. 2414 - 2428

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Citation Number: 20

Abstract

Abstract: An annelation approach to the synthesis of eudesmane sesquiterpenes is described. The 1, 6-annelation reagent a-car-bomethoxy-P-methyl-y-methylidene-An,@- butenolide (1) is used to construct the linear tricyclic lactone 2, 5, 6, 7, 8, 8a, 9, 9a@- octahydro-8aP-methyl-2-oxonaphtho [2, 3-b] furan-3-carboxylic acid methyl ester (2). The conversion of 2 to dl-dihydrocallitrisin (3), dl-7, 8-epialantolactone (4), dl-7, 8- ...