Synthesis and Biological Activity of New 3-Hydroxy-3-methylglutaryl-CoA Synthase Inhibitors: 2-Oxetanones with a Side Chain Mimicking the Extended Structure of …

橋詰博一, 伊藤元, 森川忠則, 金谷直明…

Index: Hashizume; Ito; Morikawa; Kanaya; Nagashima; Usui; Tomoda; Sunazuka; Kumagai; Omura Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 10 p. 2097 - 2107

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Abstract

... Synthase Inhibitors: 2—Oxetanones with a Side Chain Mimicking the Extended Structure of 1233A Hirokazu HASHIZUME,*'“ Hajime ITO,“ Tadanori MORIKAWA ... Previously“) this mixture was treated with triphenyl- methyl chloride and separated into its isomers by column ...