2, 3-Diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: A structure–activity relationship study

…, D Ribeiro, A Gomes, AMS Silva, JAS Cavaleiro…

Index: Santos, Clementina M.M.; Freitas, Marisa; Ribeiro, Daniela; Gomes, Ana; Silva, Artur M.S.; Cavaleiro, Jose A.S.; Fernandes, Eduarda Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 18 p. 6776 - 6784

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Citation Number: 21

Abstract

Xanthones are a class of oxygen-containing heterocyclic compounds widely distributed in nature. The natural derivatives can present different substitutions in the xanthone core that include hydroxyl, methoxyl, prenyl and glycosyl groups. The inclusion of aryl groups has only been reported for a few synthetic derivatives, the 2, 3-diaryl moiety being recently introduced by our group. Xanthones are endowed with a broad spectrum of biological ...