Quassinoids. 2. A new approach to the BCD ring system

RV Stevens, SR Angle, K Kloc, KF Mak…

Index: Stevens, Robert V.; Angle, Steven R.; Kloc, Ken; Mak, Kok F.; Trueblood, Kenneth N.; Liu, You-Xi Journal of Organic Chemistry, 1986 , vol. 51, # 23 p. 4347 - 4353

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Citation Number: 13

Abstract

3 I+: R,: Me b: R,= CH, OMe metholology for and carried out the contruction of a model BCDE ring system in connection with a total synthesis of the potent antineoplastic, bruceantin (1)(Scheme I). In this work we present an efficient preparation of the structures 2, from which we hope to provide a general route to a variety of quassinoids.