Development of a diastereoselective phosphorylation of a complex nucleoside via dynamic kinetic resolution

K Tran, GL Beutner, M Schmidt, J Janey…

Index: Cremlyn,R.J.W. et al. Journal of the Chemical Society [Section] C: Organic, 1971 , p. 2028 - 2031

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Citation Number: 4

Abstract

... The Journal of Organic Chemistry. ... A stable phosphoramidic acid derivative is coupled to the nucleoside, in a process mediated by HATU and quinine, to deliver the coupled product in high chemical yield and good diastereoselectivity. ...