Several mono-and dialkylaminoethyl esters of 2-, 5-and 6-alkoxy-3-aminobenzoic acids were prepared and tested for both topical and conductive anesthesia. Many of these proved to be highly potent and non-irritating local anesthetics with relatively low toxicities. 2'-n- Amylaminoethyl 3-amino-5-heptoxybenzoate hydrochloride when tested topically on the rabbit cornea was shown to be 210 times as efficient (ratio of potency to toxicity) as ...
