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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Tetrahedron

Stereochemical studies of 2-hydroxychromanones by 1H NMR spectroscopy

J Borbély, V Szabó, PL Sohár

Index: Szabo, Vince; Borbely, Janos; Theisz, Edit; Borda, Jeno; Janzso, Geza Tetrahedron, 1984 , vol. 40, # 2 p. 413 - 417

Full Text: HTML

Citation Number: 10

Abstract

2-Hydroxychromanones (2a–2f) were synthesized by ring closing of 2- hydroxyacetophenones (1a, b) and 2-hyroxypropiophenones (1c–1f). In the case of 2- hydroxy-3-methyl-chromanones (2c–2f) a mixture of cis and trans isomers was obtained.

 Related Synthetic Route
1-(2'-hydroxyphenyl)-propane-1,3-dione-1,3-dioxime Structure

66665-81-4

1-(2'-hydroxyph...

~0%

2,2'-[Hydroxyiminobis(4,5-dihydroisoxazole-5,3-diyl)]bisphenol Structure

65479-04-1

2,2'-[Hydroxyim...

2-ISOXAZOL-3-YL-PHENOL Structure

61348-48-9

2-ISOXAZOL-3-YL...

4H-1-Benzopyran-4-one,oxime Structure

61348-46-7

4H-1-Benzopyran...

Detail
1-(2'-hydroxyphenyl)-propane-1,3-dione-1,3-dioxime Structure

66665-81-4

1-(2'-hydroxyph...

~58%

2,2'-[Hydroxyiminobis(4,5-dihydroisoxazole-5,3-diyl)]bisphenol Structure

65479-04-1

2,2'-[Hydroxyim...

1-(2'-hydroxyphenyl)-propane-1,3-dione-1,3-dioxime Structure

66665-81-4

1-(2'-hydroxyph...

~28%

2,2'-[Hydroxyiminobis(4,5-dihydroisoxazole-5,3-diyl)]bisphenol Structure

65479-04-1

2,2'-[Hydroxyim...

2-ISOXAZOL-3-YL-PHENOL Structure

61348-48-9

2-ISOXAZOL-3-YL...

4H-1-Benzopyran-4-one,oxime Structure

61348-46-7

4H-1-Benzopyran...

Detail
2-hydroxy-2,3-dihydrochromen-4-one Structure

57669-32-6

2-hydroxy-2,3-d...

~%

2,2'-[Hydroxyiminobis(4,5-dihydroisoxazole-5,3-diyl)]bisphenol Structure

65479-04-1

2,2'-[Hydroxyim...

1-(2'-hydroxyphenyl)-propane-1,3-dione-1,3-dioxime Structure

66665-81-4

1-(2'-hydroxyph...

~32%

2,2'-[Hydroxyiminobis(4,5-dihydroisoxazole-5,3-diyl)]bisphenol Structure

65479-04-1

2,2'-[Hydroxyim...

2-ISOXAZOL-3-YL-PHENOL Structure

61348-48-9

2-ISOXAZOL-3-YL...

4H-1-Benzopyran-4-one,oxime Structure

61348-46-7

4H-1-Benzopyran...

Detail
2,2'-[Hydroxyiminobis(4,5-dihydroisoxazole-5,3-diyl)]bisphenol Structure

65479-04-1

2,2'-[Hydroxyim...

~35%

2-ISOXAZOL-3-YL-PHENOL Structure

61348-48-9

2-ISOXAZOL-3-YL...

1-(2'-hydroxyphenyl)-propane-1,3-dione-1,3-dioxime Structure

66665-81-4

1-(2'-hydroxyph...

6-(5-hydroxy-1,2-oxazolidin-3-ylidene)cyclohexa-2,4-dien-1-one Structure

89814-12-0

6-(5-hydroxy-1,...

1-(2'-hydroxyphenyl)-propane-1,3-dione-1,3-dioxime Structure

66665-81-4

1-(2'-hydroxyph...

~0%

2,2'-[Hydroxyiminobis(4,5-dihydroisoxazole-5,3-diyl)]bisphenol Structure

65479-04-1

2,2'-[Hydroxyim...

2-ISOXAZOL-3-YL-PHENOL Structure

61348-48-9

2-ISOXAZOL-3-YL...

4H-1-Benzopyran-4-one,oxime Structure

61348-46-7

4H-1-Benzopyran...

Detail
2,2'-[Hydroxyiminobis(4,5-dihydroisoxazole-5,3-diyl)]bisphenol Structure

65479-04-1

2,2'-[Hydroxyim...

~0%

2-ISOXAZOL-3-YL-PHENOL Structure

61348-48-9

2-ISOXAZOL-3-YL...

1-(2'-hydroxyphenyl)-propane-1,3-dione-1,3-dioxime Structure

66665-81-4

1-(2'-hydroxyph...

6-(5-hydroxy-1,2-oxazolidin-3-ylidene)cyclohexa-2,4-dien-1-one Structure

89814-12-0

6-(5-hydroxy-1,...

Related Articles: More...
Examination of the ring-chain isomerism of 2-hydroxy-chroman...

[Szabo, Vince; Borbely, Janos; Theisz, Edit; Janzso, Geza Tetrahedron Letters, 1982 , vol. 23, # 50 p. 5347 - 5350]
Reaction of chromones with hydroxylamine in anhydrous methan...

[Szabo, Vince; Borbely, Janos; Theisz, Edit; Nagy, Sandor Tetrahedron, 1986 , vol. 42, # 15 p. 4215 - 4222]
Reaction of chromones with hydroxylamine in anhydrous methan...

[Szabo, Vince; Borbely, Janos; Theisz, Edit; Nagy, Sandor Tetrahedron, 1986 , vol. 42, # 15 p. 4215 - 4222]
Examination of the ring-chain isomerism of 2-hydroxy-chroman...

[Szabo, Vince; Borbely, Janos; Theisz, Edit; Janzso, Geza Tetrahedron Letters, 1982 , vol. 23, # 50 p. 5347 - 5350]

Detail Synthetic Route


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