Tetrahedron letters

Regioselective electrophilic trifluoromethylation of substituted anilines and derivatives in superacid

S Debarge, B Violeau, N Bendaoud, MP Jouannetaud…

Index: Debarge, Sebastien; Violeau, Bruno; Bendaoud, Nohair; Jacquesy, Jean-Claude Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1747 - 1750

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Citation Number: 21

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... In a one pot procedure, treatment of chloro or methyl substituted acetanilides in HF/SbF 5 /CCl 4 followed by addition of HF/pyridine yields trifluoromethyl derivatives with high regioselectivity. ... Trifluoromethylated aromatics are of major importance and have found a large number of uses as ...