The Journal of Organic Chemistry

2-Oxazolidinones from an N-dealkylation reaction of phosgene with dialkylaminoalkanols. Isolation and reactivities of an N-acyl quaternary ammonium intermediate

KC Murdock

Index: Murdock,K.C. Journal of Organic Chemistry, 1968 , vol. 33, # 4 p. 1367 - 1371

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Citation Number: 14

Abstract

This report describes the isolation of a very reactive N-acyl ammonium analog of 2 and a study of its reactions with some representative nucleophiles. The scope of a novel synthesis of 2-oxazolidinones from phosgene and 2-dialkylaminoalkanols has also been explored. When equimolar amounts of l-dimethylamino-2-propanol and pyridine were added to excess phosgene in methylene chloride solution at<-40", then allowed to come to room ...