Synthesis and diuretic activity of imidazo [2, 1-b] thiazole acetohydrazones

…, M Rambaldi, G Mascellani, P Rugarli

Index: Andreani; Rambaldi; Mascellani; Rugarli European Journal of Medicinal Chemistry, 1987 , vol. 22, # 1 p. 19 - 22

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Citation Number: 51

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The synthesis of dimethylaminoacetohydrazones of 5-formylimidazo[2,1-b]thiazoles and thiazolines is reported. A potent diuretic activity was confirmed for the 2-methyl derivative bearing a phenyl ring at position 6 (4 1 ). ... Synthèse de diméthyl-aminoacétohydrazones de formyl-5 ...

 Related Synthetic Route
2-(dimethylamino)acetohydrazide Structure

55-85-6

2-(dimethylamin...

6-chloroimidazo[2,1-b]thiazole-5-carboxaldehyde Structure

23576-84-3

6-chloroimidazo...

~%

N-[(E)-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylideneamino]-2-(dimethylamino)acetamide Structure

102410-20-8

N-[(E)-(6-chlor...

2-(dimethylamino)acetohydrazide Structure

55-85-6

2-(dimethylamin...

7-(4-chlorophenyl)-4-thia-1,6-diazabicyclo[3.3.0]octa-2,5,7-triene-8-carbaldehyde Structure

82588-41-8

7-(4-chlorophen...

~%

N-[(E)-[6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylideneamino]-2-(dimethylamino)acetamide Structure

102410-33-3

N-[(E)-[6-(4-ch...

2-(dimethylamino)acetohydrazide Structure

55-85-6

2-(dimethylamin...

7-(4-methylphenyl)-4-thia-1,6-diazabicyclo[3.3.0]octa-2,5,7-triene-8-carbaldehyde Structure

82588-42-9

7-(4-methylphen...

~%

2-(dimethylamino)-N-[(E)-[6-(4-methylphenyl)imidazo[2,1-b][1,3]thiazol-5-yl]methylideneamino]acetamide Structure

102410-34-4

2-(dimethylamin...

2-(dimethylamino)acetohydrazide Structure

55-85-6

2-(dimethylamin...

3-(4-chlorophenyl)-6-thia-1,4-diazabicyclo[3.3.0]octa-2,4-diene-2-carbaldehyde Structure

82588-44-1

3-(4-chlorophen...

~%

N-[(E)-[6-(4-chlorophenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl]methylideneamino]-2-(dimethylamino)acetamide Structure

102410-38-8

N-[(E)-[6-(4-ch...

2-(dimethylamino)acetohydrazide Structure

55-85-6

2-(dimethylamin...

6-Methylimidazo[2,1-b]thiazole-5-carbaldehyde Structure

75001-31-9

6-Methylimidazo...

~%

2-(dimethylamino)-N-[(E)-(6-methylimidazo[2,1-b][1,3]thiazol-5-yl)methylideneamino]acetamide Structure

102410-31-1

2-(dimethylamin...

2-(dimethylamino)acetohydrazide Structure

55-85-6

2-(dimethylamin...

6-Phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazole-5-carbaldehyde Structure

75224-64-5

6-Phenyl-2,3-di...

~%

2-(dimethylamino)-N-[(E)-(6-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methylideneamino]acetamide Structure

102410-36-6

2-(dimethylamin...


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