Analytical chemistry

Native chemical ligation combined with spirocyclization of benzopyrylium dyes for the ratiometric and selective fluorescence detection of cysteine and homocysteine

H Lv, XF Yang, Y Zhong, Y Guo, Z Li, H Li

Index: Wang, Ting; Zhao, Qing-Jie; Hu, Hong-Gang; Yu, Shi-Chong; Liu, Xiang; Liu, Li; Wu, Qiu-Ye Chemical Communications, 2012 , vol. 48, # 70 p. 8781 - 8783

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Citation Number: 61

Abstract

Spirocyclization of xanthene dyes has become a powerful technique for developing fluorescent probes. Herein, we extend this unique fluorescence switching mechanism to a near-infrared (NIR) dye, 2-(7-diethylamino-2-oxo-2H-1-benzopyran-3-yl)-4-(2-