Tetrahedron

Controlled mono-and double-Heck reaction catalyzed by a dicarbene dipalladium complex

Y Li, G Liu, C Cao, S Wang, Y Li, G Pang, Y Shi

Index: Li, Yunfei; Liu, Gang; Cao, Changsheng; Wang, Shuzhan; Li, Yuling; Pang, Guangsheng; Shi, Yanhui Tetrahedron, 2013 , vol. 69, # 30 p. 6241 - 6250

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Citation Number: 9

Abstract

The phosphine-free mono-and double-Heck reaction of terminal olefins with electron- deficient and electron-rich aryl halides (iodides and bromides) is described. These reactions are catalyzed by the dicarbene dipalladium complex 1 by controlling the stoichiometry of the aryl halide and the olefine, the loading of the palladium catalyst, as well as using different base, and with or without additive. The procedure of double-Heck reaction allows β, β- ...