Quantitative structure-antifungal activity relationships of some benzohydrazides against Botrytis cinerea

…, L Saiz-Urra, R Hernández-Galán…

Index: Reino, Jose L.; Saiz-Urra, Liane; Hernandez-Galan, Rosario; Aran, Vicente J.; Hitchcock, Peter B.; Hanson, James R.; Gonzalez, Maykel Perez; Collado, Isidro G. Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 13 p. 5171 - 5179

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Citation Number: 6

Abstract

Fourteen benzohydrazides have been synthesized and evaluated for their in vitro antifungal activity against the phytopathogenic fungus Botrytis cinerea. The best antifungal activity was observed for the N', N'-dibenzylbenzohydrazides 3b-d and for the N-aminoisoindoline- derived benzohydrazide 5. A quantitative structure-activity relationship (QSAR) study has been developed using a topological substructural molecular design (TOPS-MODE) ...