Tetrahedron Letters

Total synthesis of the elemanolides (±) zempoalin A and B

S Bartel, F Bohlmann

Index: Bartel, S.; Bohlmann, F. Tetrahedron Letters, 1989 , vol. 30, # 6 p. 685 - 688

Full Text: HTML

Citation Number: 14

Abstract

Abstract Starting with a suitable trisubstituted cyclohexanone derivative two further substituents were introduced via an epoxy ketone which after reduction was reacted with the diethylaluminium derivative of ethoxyacetylene. The resulting dihydroxyester afforded the corresponding cis-lactone which could be transformed to (±) zempoalin A and B in the usual way via selenium chemistry.