Isoxazolo [3, 4-b] quinoline-3, 4 (1H, 9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular …

Y Tong, KD Stewart, S Thomas, M Przytulinska…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 19 p. 5206 - 5208

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Citation Number: 44

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... Here, we report our medicinal chemistry efforts leading to a novel class of potent and selective inhibitors against both Pim-1 and Pim-2 kinases. ...