Bolaamphiphiles and monolayer lipid membranes made from 1, 6, 19, 24-tetraoxa-3, 21-cyclohexatriacontadiene-2, 5, 20, 23-tetrone

…, HH David, J Mathieu, U Liman, HJ Winter…

Index: Fuhrhop, Juergen-Hinrich; David, Hans-Hermann; Mathieu, Joachim; Liman, Ulrich; Winter, Hans-Joerg; Boekema, Egbert Journal of the American Chemical Society, 1986 , vol. 108, # 8 p. 1785 - 1791

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Citation Number: 161

Abstract

Abstract: The title macrotetrolide contains two maleic diester units that add hydrophilic sulfur nucleophiles, e+, bisulfite, thioacetic acid, and various thioglycosides, in high yield. Two- headed amphiphiles (“bolaamphiphiles” or “bolytes”) are thus formed. They produce extremely thin (hydrophobic part-20%.) monolayer lipid membrane (MLMs) vesicles, which have been characterized by electron microscopy. Vesicle MLMs produce well-resolved 'H ...