The Combination of 1-Butyl-3-methylimidazolium Bromide and Trichloro (trifluoromethanesulfonato) titanium (IV) as a New Protocol for the Synthesis of Aryl …

J Noei, AR Khosropour, A Mirjafari

Index: Noei, Jalil; Khosropour, Ahmad Reza; Mirjafari, Arsalan Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 6 p. 2102 - 2104

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Citation Number: 4

Abstract

Nitriles are one of the most important precursors in organic synthesis. These compounds are used for the preparation of esters, 1 amides, 1, 2 carboxylic acids, 1, 3 amines 1, 4 and thioamides. 5 Nitriles have also found widespread application in preparation of heterocycles as tetrazoles. 6 The classical method for the synthesis of alkyl nitriles is the reaction of alkyl halides with highly toxic metal cyanide via a nucleophilic pathway. However, this reaction ...