Synthesis and SAR of highly potent dual 5-HT 1A and 5-HT 1B antagonists as potential antidepressant drugs

A Kling, UEW Lange, H Mack, MHM Bakker…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 24 p. 5567 - 5573

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Citation Number: 22

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... 9 Hence, there is a large medical need for the development of novel antidepressants with improved efficacy, faster onset of action, and better tolerability. ...