e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Journal of the Chemical Society C: Organic
Syntheses with isoxazoles; the production of an isoxazolo [2, 3-a] pyridinium salt, and the photochemical conversion of isoxazole-3-carboxylates into oxazole-2- …
RH Good, G Jones
Index: Good,R.H.; Jones,G. Journal of the Chemical Society [Section] C: Organic, 1971 , p. 1196 - 1198
Cyclisation of 3-(4-ethoxybutyryl) isoxazole (6) gave 4, 5, 6, 7-tetrahydro-4-oxoisoxazolo [2, 3-a] pyridinium bromide (7). An attempt to aromatise the ketone (7) with boiling acetic anhydride was unsuccessful, but bromination gave a dibromo-ketone (9), which was dehydrobrominated to 5-bromo-4-hydroxyisoxazolo [2, 3-a] pyridinium bromide (10). The photochemical conversion of isoxazole-3-carboxylates into the corresponding oxazole-2- ...
