A series of new N-heterocyclic derivatives of 1-phenol-4-sulfonamide and p- halogenobenzenesulfonamide have been synthesized for screening as chemotherapeutic agents. In the course of this investigation, variations were made in the heterocyclic radical and the substituents on the heterocycle and on the benzene ring; and certain related types were synthesized, such as N-heterocyclic-p-methoxybenzenesulfonamides, N-guanyl-1- ...