J. Chem. Soc., Perkin Trans. 1

Amino acids bearing nucleobases for the synthesis of novel peptidenucleic acids

G Lowe, T Vilaivan

Index: Lowe, Gordon; Vilaivan, Tirayut Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 4 p. 539 - 546

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Citation Number: 91

Abstract

All of the four nucleobases found in DNA have been incorporated in their protected form into the 4-position of N-tert-butoxycarbonyl-L-proline methyl ester with cis-stereochemistry. An efficient route for the synthesis of N-tert-butoxycarbonyl-trans-4-hydroxy--proline methyl ester has been developed from which the