Discovery of aminofurazan-azabenzimidazoles as inhibitors of Rho-kinase with high kinase selectivity and antihypertensive activity

RA Stavenger, H Cui, SE Dowdell…

Index: Journal of Medicinal Chemistry, , vol. 50, # 1 p. 2 - 5

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Citation Number: 66

Abstract

... Journal of Medicinal ... Departments of Medicinal Chemistry, Investigative Biology, Vascular Biology, and Drug Metabolism and Pharmacokinetics, CVU ... and Department of Assay Development and Compound Profiling and High-Throughput Chemistry, GlaxoSmithKline, Research ...