Studies on Arginine Peptides. II. Synthesis of L-Arginyl-L-arginine and other N-Terminal Arginine Dipeptides

L Zervas, TT Otani, M Winitz…

Index: Zervas et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 2878,2881

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Citation Number: 44

Abstract

N~. Nw-Dicarbobenzoxy-L-arginine and tricarbobenzoxy-L-arginine have been utilized for the preparation of a variety of dipeptides containing an N-terniinal arginine residue. The former compound, either as its acid chloride-hydrochloride derivative or under the condensing action of dicpclohexylcarbodiimide, was coupled with diethyl glutamate and the condensation. product subsequently converted to the corresponding free peptide ma ...