Factors were investigated which govern nucleophilic reactivities of functional groups in aminothiols, thiols, and other model compounds with &-unsaturated compounds such as acrylonitrile. Rates as a function of p H correlate with theoretical rate equations and indicate that mercaptide ions and nonprotonated amino groups participate in the rate-determining step. Possible reaction pathways of aminothiols are considered in terms of the two ...
