New sources are constantly being explored to identify scaffolds which can help in finding cures for diseases affecting human beings. Marine organisms have provided some potent and complex compounds which are being explored as leads for better healthcare. 1 In 2009, Fenical et al. reported, from the extracts of Salinispora arenicola strain CNT-088, the isolation, structural elucidation and NFκB inhibition activities of three cyclic depsipeptides and named them arenamides ...