5-Substituted-1-indancarboxylic acids as potential antiinflammatory agents

…, R Littell, FJ McEvoy, AE Sloboda

Index: Allen Jr.; Littell; McEvoy; Sloboda Journal of medicinal chemistry, 1972 , vol. 15, # 9 p. 934 - 937

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Citation Number: 14

Abstract

In view of our interests'6 in analogs of nonsteroidal antiinflammatory agents in which the carboxylic acid group is fmed conformationally, we have prepared certain 5- alkylindancarboxylic acids for testing as antiinflammatory agents. Independent of our efforts, two other laboratories have prepared the most apparent analog of this type, ie, 6-chloro-5- cyclohexylindan-1-carboxylic acid (S), and reported on its antiinflammatory properties.”,' ...