Development of 4-aminoquinoline-1, 3, 5-triazine conjugates as potent antibacterial agent through facile synthetic route

HR Bhat, PK Pandey, SK Ghosh, UP Singh

Index: Bhat, Hans Raj; Pandey, Pankaj Kumar; Ghosh, Surajit Kumar; Singh, Udaya Pratap Medicinal Chemistry Research, 2013 , vol. 22, # 10 p. 5056 - 5065

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Citation Number: 8

Abstract

Abstract A series of novel hybrid 4-aminoquinoline-1, 3, 5-triazine derivatives were developed and subsequently tested against representative Gram-positive and Gram- negative microorganisms for determination of their antibacterial activity. Screening results indicate that, title molecule exhibit moderate to potent activity in comparison to standard. These hybrid derivatives were synthesized through a facile synthetic routes and structure ...