Synthetic Communications

Aqueous 1 M glucose solution as a novel and fully green reaction medium and catalyst for the oxidant-free synthesis of 2-arylbenzimidazoles

S Rostamizadeh, R Aryan…

Index: Rostamizadeh, Shahnaz; Aryan, Reza; Ghaieni, Hamid Reza Synthetic Communications, 2011 , vol. 41, # 12 p. 1794 - 1804

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Citation Number: 11

Abstract

Abstract The reaction of various o-phenylenediamines and substituted benzaldehydes was carried out in 1 M glucose solution as reaction medium and catalyst under one-pot oxidant- free conditions. The desired products were obtained at 60° C with good to excellent yields, and the reaction was performed chemoselectively without formation of 1, 2-disubstituted benzimidazoles. No need for any extra oxidant, simple workup, and use of carbohydrates ...