A useful Wittig reagent for the stereoselective synthesis of trans-. alpha.,. beta.-unsaturated thiol esters

GE Keck, EP Boden, SA Mabury

Index: Keck, Gary E.; Boden, Eugene P.; Mabury, Scott A. Journal of Organic Chemistry, 1985 , vol. 50, # 5 p. 709 - 710

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Citation Number: 45

Abstract

The reaction of aldehydes with Wittig reagents of the general structure (Ph) 3PCHC02R constitutes an extremely powerful method for two-carbon chain extension which has seen wide application. The corresponding phosphonates,(R0) 2P (0) CH2C02R', are also very useful reagents in the same context. However, several problems can arise upon application of the above reagents to complex systems. For instance, the phosphoranes often exhibit ...

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Electron-transfer processes. 43. Attack of alkyl radicals up...

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