New functionalised silicas for highly selective cation exchange SPE purification in medicinal chemistry

J Brown, A Chighine, MA Colucci, N Galaffu, SC Hirst…

Index: Tetrahedron Letters, , vol. 49, # 33 p. 4968 - 4971

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Citation Number: 5

Abstract

... Tetrahedron Letters. Volume 49, Issue 33, 11 August 2008, Pages 4968–4971. ... using this approach, and which feature sulfonic acid 1, 11 phosphonic acid 2 and carboxylic acid functionalities, leading to coverage of apK a range from approximately 1–6. For this Letter, our efforts ...