e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis, characterisation and anti-protozoal activity of carbamate-derived polyazamacrocycles
JM Wilson, F Giordani, LJ Farrugia…
Index: Wilson, Jennifer M.; Giordani, Federica; Farrugia, Louis J.; Barrett, Michael P.; Robins, David J.; Sutherland, Andrew Organic and Biomolecular Chemistry, 2007 , vol. 5, # 22 p. 3651 - 3656
A short, highly efficient approach for the synthesis of a novel class of polyazamacrocycles containing N-functionalised carbamate side-chains has been developed. The key steps involved a phase-transfer mediated macrocyclisation to form the ring system as well as a tin- catalysed reaction with isocyanates to introduce the carbamate side-chains. X-Ray crystallography confirmed successful formation of the 1, 4, 7, 10-tetraazacyclododecane ...
![Benzenesulfonamide,4-methyl-N,N-bis[2-[[(4-methylphenyl)sulfonyl]amino]ethyl]- Structure](https://image.chemsrc.com/caspic/348/56187-04-3.png)
![2-[4,7,10-tris(2-hydroxyethyl)-1,4,7,10-tetrazacyclododec-1-yl]ethanol Structure](https://image.chemsrc.com/caspic/486/67896-40-6.png)
