Efficient diverse approach for quinoxaline??derived glycosylated and morphinylated analogs

…, KF Atta, S Aboul??Ela, ESH El Ashry

Index: Beldi, Razika; Atta, Kamal F.; Aboul-Ela, Sallah; El Ashry, El Sayed H. Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 1 p. 50 - 56

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Citation Number: 3

Abstract

Abstract Sulfanyl-glycosides have been synthesized by reaction of 2, 3- dimercaptoquinoxaline (1) with acetohalo sugars in presence of base to give the thioglycosides-derived quinoxalines 5, 6, 7 and 9. Similarly, the acyclic analogs 23, 24, 25, 26 were prepared by coupling of 1 with different acyclo-alkylating agents. The preparation of 3-morpholinyl-quinoxalines 10 and 11 allowed the synthesis of 3-glycosylsulfanyl-2- ...