Synthesis and Antibacterial Activity of Aromatic and Heteroaromatic Amino Alcohols

…, AM de Almeida, CG Diniz, VL da Silva…

Index: de Almeida, Camila G.; Reis, Samira G.; de Almeida, Angelina M.; Diniz, Claudio G.; da Silva, Vania L.; Le Hyaric, Mireille Chemical Biology and Drug Design, 2011 , vol. 78, # 5 p. 876 - 880

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Citation Number: 10

Abstract

Two series of aromatic and heteroaromatic amino alcohols were synthesized from alcohols and aldehydes and evaluated for their antibacterial activities. All the octylated compounds displayed a better activity against the four bacteria tested when evaluated by the agar diffusion method and were selected for the evaluation of minimal inhibitory concentration. The best results were obtained for p-octyloxybenzyl derivatives against Staphylococcus ...