AMP deaminase inhibitors. 3. SAR of 3-(carboxyarylalkyl) coformycin aglycon analogues

SR Kasibhatla, BC Bookser, G Probst…

Index: Journal of Medicinal Chemistry, , vol. 43, # 8 p. 1508 - 1518

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Citation Number: 25

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. The AMPDA inhibitor analogues (Tables 1 and 2) were prepared using the general three-step procedure outlined in Scheme 1. Alkylation of the heterocycle 6,7-dihydroimidazo ...