Pyrazolo [1, 5-a] pyrimidines, triazolo [1, 5-a] pyrimidines and their tricyclic derivatives as corticotropin-releasing factor 1 (CRF 1) receptor antagonists

T Saito, T Obitsu, C Minamoto, T Sugiura…

Index: Bioorganic and Medicinal Chemistry, , vol. 19, # 20 p. 5955 - 5966

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Citation Number: 21

Abstract

... Bioorganic & Medicinal Chemistry. ... Significant contributions have been made in the past two decades by several pharmaceutical research groups to discover non-peptide CRF 1 receptor antagonists as a potential treatment for stress-related illnesses (including depression). ...