Synthesis and pharmacological evaluation of some novel 2-(5-hydroxy-5-trifluoromethyl-4, 5-dihydropyrazol-1-yl)-4-(coumarin-3-yl) thiazoles

R Aggarwal, S Kumar, P Kaushik, D Kaushik…

Index: European Journal of Medicinal Chemistry, , vol. 62, p. 508 - 514

Full Text: HTML

Citation Number: 38

Abstract

... European Journal of Medicinal Chemistry. ... The 1 H NMR spectra of 6 displayed two doublets appearing at about δ 3.85 (J HA–HB = 18–21 Hz) and δ 3.70 ppm (J HA–HB = 18–21 Hz) (about δ 3.73 and 3.55 ppm for 6a–c) due to geminal coupling of H B with H A at position-4 ...