Synthesis

Carbon tetrabromide promoted reaction of amines with carbon disulfide: facile and efficient synthesis of thioureas and thiuram disulfides

F Liang, J Tan, C Piao, Q Liu

Index: Liang, Fushun; Tan, Jing; Piao, Chengri; Liu, Qun Synthesis, 2008 , # 22 p. 3579 - 3584

Full Text: HTML

Citation Number: 11

Abstract

Abstract A novel carbon tetrabromide promoted one-pot reaction of amines and carbon disulfide under mild conditions has been developed, which provides a straightforward and efficient access to thioureas and thiuram disufides, depending on the nature of the amines employed. The promotion effect is explained as the transient formation of a sulfenyl bromide intermediate from dithiocarbamate and carbon tetrabromide during the reaction.