A structure–activity analysis of biased agonism at the dopamine D2 receptor

J Shonberg, CK Herenbrink, L López…

Index: Journal of Medicinal Chemistry, , vol. 56, # 22 p. 9199 - 9221

Full Text: HTML

Citation Number: 37

Abstract

... Journal of Medicinal Chemistry. ... Medicinal Chemistry, ‡ Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash ... Abstract. Abstract Image. Biased agonism offers an opportunity for the medicinal chemist to discover pathway-selective ligands for GPCRs. ...

Identification of C-2 hydroxyethyl imidazopyrrolopyridines a...

[Zak, Mark; Hurley, Christopher A.; Ward, Stuart I.; Bergeron, Philippe; Barrett, Kathy; Balazs, Mercedesz; Blair, Wade S.; Bull, Richard; Chakravarty, Paroma; Chang, Christine; Crackett, Peter; Deshmukh, Gauri; Devoss, Jason; Dragovich, Peter S.; Eigenbrot, Charles; Ellwood, Charles; Gaines, Simon; Ghilardi, Nico; Gibbons, Paul; Gradl, Stefan; Gribling, Peter; Hamman, Chris; Harstad, Eric; Hewitt, Peter; Johnson, Adam; Johnson, Tony; Kenny, Jane R.; Koehler, Michael F. T.; Bir Kohli, Pawan; Labadie, Sharada; Lee, Wyne P.; Liao, Jiangpeng; Liimatta, Marya; Mendonca, Rohan; Narukulla, Raman; Pulk, Rebecca; Reeve, Austin; Savage, Scott; Shia, Steven; Steffek, Micah; Ubhayakar, Savita; Van Abbema, Anne; Aliagas, Ignacio; Avitabile-Woo, Barbara; Xiao, Yisong; Yang, Jing; Kulagowski, Janusz J. Journal of Medicinal Chemistry, 2013 , vol. 56, # 11 p. 4764 - 4785]