Chemical and Pharmaceutical Bulletin

Synthesis of Furan Derivatives. LVII. The Reaction of Keto Acetylenic Esters with Carbonyl Reagents

H SAIKACHI, T KITAGAWA

Index: Saikachi,H.; Kitagawa,T. Chemical and Pharmaceutical Bulletin, 1971 , vol. 19, p. 1562 - 1566

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Citation Number: 3

Abstract

Methyl (ethyl) 5-(2'-furyl) isoxazole-3-carboxylate (3a and 3b) were prepared frommethyl (ethyl) 2-furoylpropiolates with hydroxylamine, respectively. Methyl (ethyl) 5-(2'-furyl) pyrzaole-3-carboxylates (10a and 10b) were formed by the condensation ofmethyl (ethyl) 2- furoylpropiolates with hydrazine hydrate. The corresponding 5'-nitrofuran derivatives (4a and 11b) were obtained in usual manner, and the each position ofnitro group of the furan ...