Synthesis of montelukast (MK-0476) metabolic oxidation products

C Dufresne, M Gallant, Y Gareau, R Ruel…

Index: Journal of Organic Chemistry, , vol. 61, # 24 p. 8518 - 8525

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Citation Number: 20

Abstract

... The Journal of Organic Chemistry. ... and on the same side of the ring. The large three-bond coupling constants of 10.9 Hz for 3 J 19,20ax and 3 J 21,20ax also indicated a syn stereochemistry. In the case of 18a, a strong ...