Direct reduction of alcohols: highly chemoselective reducing system for secondary or tertiary alcohols using chlorodiphenylsilane with a catalytic amount of indium …

M Yasuda, Y Onishi, M Ueba, T Miyai…

Index: Yasuda; Onishi; Ueba; Miyai; Baba Journal of Organic Chemistry, 2001 , vol. 66, # 23 p. 7741 - 7744

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Citation Number: 139

Abstract

The direct reduction of alcohols using chlorodiphenylsilane as a hydride source in the presence of a catalytic amount of indium trichloride is described. Benzylic alcohols, secondary alcohols, and tertiary alcohols were effectively reduced to give the corresponding alkanes in high yields. A compound bearing both primary and secondary hydroxyl groups was reduced only at the secondary site to afford the primary alcohol after workup with ...