Synthesis of some bioactive acetylenic alcohols, components of the marine sponge Cribrochalina vasculum

…, S Chattopadhyay, A Chattopadhyay…

Index: Kulkarni, B. A.; Chattopadhyay, S.; Chattopadhyay, A.; Mamdapur, V. R. Journal of Organic Chemistry, 1993 , vol. 58, # 22 p. 5964 - 5966

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Citation Number: 22

Abstract

The current upsurge in marine research has rejuvenated natural product chemistry. Recently, Gunasekera and Fairclothl have isolated a series of acetylenic alcohols from the marine sponge Cribrochalina vasculum. Their potential in vitro immunosuppressive and antitumor activities and 1, 4-enyn-3-01 skeleton provided an attractive challenge for synthesis. In a continuation of our recent efforts" in this direction, we report the first ...