Tetrahedron

Synthetic applications of 2-chlorooxiranes: preparation of thiazoles, dihydrothiazoles and selenazoles

J Gasteiger, C Herzig

Index: Gasteiger, Johann; Herzig, Christian Tetrahedron, 1981 , vol. 37, # 15 p. 2607 - 2611

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Citation Number: 19

Abstract

The reaction of 2-chlorooxiranes 1 with thioamides and thioureas provides access to thiazoles, 4-hydroxy-4, 5-dihydrothiazoles and 2-imino-2, 3-dihydrothiazoles under mild conditions and with excellent yields. With 1 and selenourea, near quantitative yields of selenazoles are obtained.