e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Convenient method of esterification of polyphosphonic acids
DA Nicholson, WA Cilley…
Index: Nicholson,D.A. et al. Journal of Organic Chemistry, 1970 , vol. 35, p. 3149 - 3150 Full Text View citing articles Show Details McKenna, Charles E.; Khawli, Leslie A.; Ahmad, Wan-Yaacob; Pham, Phuong; Bongartz, Jean-Pierre Phosphorus and Sulfur and the Related Elements, 1988 , vol. 37, p. 1 - 12
Unlike carboxylic acids, phosphonic acids cannot be esterified by direct reaction with alcohols. Esterification is usually accomplished by converting the phosphonic acid to the corresponding acid chloride which will react with an alcohol in the presence of base to yield the phosphonate ester. 2